★ 40 La Zisa (Zisa Palace)

The structure includes Islamic elements such as muqarnas, and vaulted niches. In the 14th century merlons were added, by partly destroying the Arab inscription (in Kufic characters) which embellished the upper part of the building. More substantial modifications were introduced in the 17th century, when the Zisa, reduced to very poor conditions, was purchased by Giovanni di Sandoval e Platamone, Marquis of S. Giovanni la Mendola, Prince of Castelreale, Lord of the Mezzagrana and the Zisa. The latter's marble coat of arms with two lions can be seen over the entrance fornix. Several rooms of the interior were modified and others added on the ceiling, a great stair was built, as well as new external windows.

As the Zisa was originally built as a semi-rural summer palace, many of its design features reflect this function. A pool at the front of the building flowed through open channels into the interior to the main hall. The architect chose to use thicker material for building and smaller windows to keep a stable internal temperature. The castle had a fully functional air conditioning system that allowed airflow throughout the whole of the building that was heavily inspired by Egyptian and Mesopotamian architectural styles and the architect also made the conscious choice to build the building facing towards the ocean.